Hotels in Clayton, MO
Search and compare Clayton, MO hotels from hundreds of travel sites on HotelsCombined and save.
Clayton, United States
Apr 24 — Apr 252
...and more
Learn why travelers love HotelsCombined
Travel insights for hotels in Clayton
Use our HotelsCombined data-powered tips to help you find your next hotel in Clayton.
What is the cheapest month to book a hotel in Clayton?
The cheapest month to book a hotel in Clayton is October ($176). Conversely, the most expensive month to stay in Clayton is May ($342).
What is the cheapest day to stay in a hotel in Clayton?
The cheapest day to stay in Clayton is Sunday ($165). On the other hand, travelers can expect to pay the most on Monday, when the average nightly price is $314.
Cheapest hotels in Clayton, MO
Discover affordable stays in Clayton, MO that provide a quality experience without breaking the bank. Hotels in Clayton, MO can be found for as low as $123 per night. There is currently one property in Clayton, MO that can be booked for this price. Clayton Plaza Hotel is one of the hotels that can be booked for the lowest price in Clayton, MO. Price data was last updated on April 17, 2025
These Clayton properties charge the lowest price per night of those we've come across. If you have flexibility with arrival and departure, use the search form to compare prices for other dates.
Show all 6 hotels
7750 Carondelet Avenue, Clayton, MO, United States
0.3 mi from city centre
Pool
Free Wi-Fi
$123
Avg. per night
216 N Meramec Avenue, Clayton, MO, United States
0.6 mi from city centre
Pool
Free Wi-Fi
$159
Avg. per night